The effectiveness and tolerability of trauma-focused interventions for trauma symptoms in individuals who have psychosis: A systematic review and meta-analysis.

Schizophr ResJun 12, 2026 (epub)
Clinical ResearchPsychiatry

Ava Mason, Yanakan Logeswaran, Felix Opper et al.

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In 30 seconds

This systematic review and meta-analysis evaluated the effectiveness and tolerability of trauma-focused therapies (TFTs) for individuals with psychosis. Ten randomized controlled trials were included, revealing that Eye Movement Desensitization and Reprocessing (EMDR) significantly reduced PTSD symptoms post-treatment (g = 0.84, p < 0.001) and at 6-month follow-up (g = 0.63, p < 0.001) compared to treatment-as-usual.

Key findings

  • EMDR significantly reduced positive psychotic symptoms post-treatment (g = 0.21, p = 0.05).
  • EMDR significantly reduced PTSD symptoms post-treatment (g = 0.84, p < 0.001).
  • EMDR maintained significant reductions in PTSD symptoms at 6-month follow-up (g = 0.63, p < 0.001).
  • Prolonged exposure (PE) and cognitive therapies (CR) also showed reductions in PTSD symptoms.

Why it matters

Individuals with psychosis and a history of trauma often experience worse clinical outcomes. Effective trauma-focused interventions can improve their mental health and overall functioning, making it crucial for clinicians to consider these therapies in treatment plans.

Source

Published in Schizophr Res. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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