Pneumatic Balloon Dilation versus Heller's Myotomy in Pediatric Achalasia: A Systematic Review and Meta-Analysis.
Marcella M Constante, Kayla D Santos, Letizia Corbi et al.
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In 30 seconds
This systematic review and meta-analysis compared pneumatic balloon dilation (PBD) and Heller's myotomy (HM) for treating achalasia in children. Analyzing data from nine observational studies involving 317 patients, HM was linked to significantly lower odds of reoperation (OR = 11.01) and symptom recurrence (OR = 8.00), while PBD was associated with a reduced risk of gastroesophageal reflux disease (OR = 0.14).
Key findings
- Heller's myotomy was associated with lower odds of reoperation (OR = 11.01).
- Heller's myotomy also showed lower odds of symptom recurrence (OR = 8.00).
- Pneumatic balloon dilation was linked to a lower risk of gastroesophageal reflux disease (OR = 0.14).
- No significant differences were found in perforation rates between the two interventions.
Why it matters
Understanding the comparative effectiveness of PBD and HM in pediatric achalasia is crucial for optimizing treatment strategies and improving patient outcomes. This analysis highlights the potential benefits and risks associated with each intervention.
What to keep in mind
All included studies were retrospective cohorts with heterogeneous reporting of techniques and outcomes.