Extranodal NK/T-Cell Lymphoma Revealed by Hemophagocytic Lymphohistiocytosis: A Case Report.

Int J Lab HematolJun 12, 2026 (epub)
Case ReportHematologyOncology (Medical)Pathology (Anatomic & Clinical)

Clara Assadi-Gazvini, Chloé Li, Pierre Arnautou et al.

✦ AI-curated · Sources linked

Case in brief

A 67-year-old man presented with compressive aerodigestive symptoms and cytopenias. Evaluation identified hemophagocytic lymphohistiocytosis (HLH), which led to recognition of extranodal NK/T-cell lymphoma, nasal type. Bone marrow and lymph node biopsies confirmed the lymphoma. He was treated with immunochemotherapy combining etoposide and pembrolizumab.

What made this case unusual

HLH revealed the lymphoma, presenting alongside compressive aerodigestive symptoms and cytopenias.

Diagnostic / clinical pearl

In a patient with HLH, cytopenias and compressive aerodigestive symptoms, consider an underlying lymphoma; tissue diagnosis may require bone marrow and lymph node biopsy.

Source

PubMed · PMID 42285774

Published in Int J Lab Hematol. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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