Identification and pathogenicity validation of a novel MLH1 frameshift mutation in Lynch syndrome pedigree.

GeneJun 13, 2026 (epub)

Dayang Zhou, Chang Liu, Wenjing Xu et al.

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Condensed from the publisher's abstract. An xxcode editorial summary of this publication has not been generated yet.

From the abstract

Lynch syndrome (LS), the most prevalent hereditary colorectal cancer (CRC) syndrome, accounts for approximately 2 %-3 % of all CRC cases and confers a significantly elevated cancer risk among affected family members, necessitating targeted preventive interventions.

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Published in Gene. The text above is extracted from the publisher's own abstract and has not been edited by xxcode. For clinical decisions, review the original publication.

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