High-intensity interval training and moderate-intensity continuous training are effective, feasible, and safe for patients with metabolic dysfunction-associated steatotic liver disease (MASLD): A systematic review and meta-analysis.
Bo Wang, Xinyu Zeng, Hengzhi Deng et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on patients with metabolic dysfunction-associated steatotic liver disease (MASLD). Involving 1546 participants, the study found that HIIT significantly improved 12 outcomes, including total cholesterol reduction (g -0.44, p < 0.05), while MICT improved 18 outcomes, demonstrating both interventions' efficacy, feasibility, and safety.
Key findings
- HIIT improved total cholesterol by g -0.44 compared to controls.
- MICT positively affected 18 outcomes, including body composition and liver markers.
- Adherence to exercise was high at 83.4%, with completion rates at 83.9%.
- Subgroup analyses revealed significant moderators like obesity status and training frequency.
Why it matters
Understanding the effectiveness of HIIT and MICT in managing MASLD can guide clinicians in developing tailored exercise prescriptions, potentially improving patient outcomes in this population.