Perioperative nutrition therapy to optimize colorectal patient outcomes: A systematic review and meta-analysis.
JPEN J Parenter Enteral NutrJun 15, 2026 (epub)
Alexander Troester, Shelbi Olson, Lindsay Welton et al.
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In 30 seconds
This systematic review and meta-analysis evaluated perioperative nutritional interventions in colorectal surgery patients. It included 27 studies and found that protein supplementation and immunonutrition may reduce surgical site infection rates compared to dietary advice alone, although the overall strength of evidence is low. The findings suggest limited benefits of these interventions on postoperative complications.
Key findings
- Protein supplementation and immunonutrition may lower surgical site infection rates compared to dietary advice alone.
- Carbohydrate loading likely shows no difference in outcomes compared to standard practices.
- Immunonutrition and carbohydrate loading probably do not affect anastomotic leak rates.
- Evidence on optimal postoperative diet is insufficient.
Why it matters
Understanding the impact of nutritional interventions on postoperative outcomes is crucial for improving recovery and reducing complications in colorectal surgery patients. This review highlights the need for further research in this area.