Impact of Life-Context Factors on Chronic Rhinosinusitis 22-Item Sinonasal Outcomes Test: Systematic Review + Meta-Analysis.
Kassandra M Jade, George A Scangas, Victoria S Lee et al.
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In 30 seconds
This systematic review and meta-analysis examined the impact of Life-Context factors on 22-item Sinonasal Outcomes Test (SNOT-22) scores in chronic rhinosinusitis (CRS) patients. Among 61 studies, females had worse baseline SNOT-22 scores (SMD = 0.30), while Medicaid and private insurance patients also reported worse scores compared to Medicare (SMD = 0.81).
Key findings
- Females had worse baseline SNOT-22 scores (SMD = 0.30, 95% CI: 0.24-0.36).
- Medicaid patients had worse baseline SNOT-22 scores compared to Medicare (SMD = 0.81, 95% CI: 0.48-1.15).
- Smokers reported worse SNOT-22 scores (SMD = 0.37, 95% CI: 0.22-0.53).
- Younger patients often had higher baseline SNOT-22 scores.
Why it matters
Understanding how Life-Context factors influence CRS outcomes can help clinicians tailor care and address disparities in treatment effectiveness. This knowledge is essential for improving patient management and ensuring equitable healthcare delivery.
What to keep in mind
Variability in studies and reporting methods limited clear conclusions, and there was a lack of comprehensive data on race, ethnicity, and other social determinants.