Uncommon Tumor, Unusual Site, and Unconventional Behavior: Report of a Gastric Composite Gangliocytoma/Neuroma and Neuroendocrine Tumor (CoGNET) With Metastases.

Int J Surg PatholJun 16, 2026 (epub)
Case ReportPathology (Anatomic & Clinical)GastroenterologyOncology (Medical)

Alicia Dessain, Vikas Prasad, Nikolaos Trikalinos et al.

✦ AI-curated · Sources linked

Case in brief

A patient was found to have a composite gangliocytoma/neuroma and neuroendocrine tumor (CoGNET) arising in the stomach, an unusual site for this entity. The tumor had distinctive histomorphologic features in the primary lesion and in metastases. The report discusses diagnostic pitfalls and emphasizes recognizing the combined features of this potentially malignant tumor. The abstract does not provide further clinical presentation, diagnostic work-up, treatment, or outcome details.

What made this case unusual

The unusual combination was gastric origin and metastases, with distinctive histomorphology in the primary tumor and metastatic lesions.

Diagnostic / clinical pearl

Recognize the combined gangliocytoma/neuroma and neuroendocrine tumor features when assessing a suspected CoGNET; the report highlights diagnostic pitfalls in this potentially malignant entity.

Source

PubMed · PMID 42300695

Published in Int J Surg Pathol. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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