Bean syndrome in childhood: Use of sirolimus in a severe case.
Nadia Dell, Nicolás Affranchino, Laura Busquet et al.
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Case in brief
A pediatric patient was diagnosed with Bean syndrome (blue rubber bleb nevus syndrome), a congenital disorder involving multiple venous malformations. Typical skin lesions and gastrointestinal involvement were identified. The report describes the clinical course, diagnostic investigations, and treatment initiated with sirolimus. The abstract does not provide further clinical findings or outcomes. It emphasizes recognition of the syndrome in children, multidisciplinary follow-up, and close monitoring during sirolimus treatment.
What made this case unusual
The report concerns a severe pediatric case treated with sirolimus; the abstract presents sirolimus as a promising option for severe disease but provides no specific treatment outcome.
Diagnostic / clinical pearl
Typical skin lesions together with gastrointestinal involvement should prompt consideration of Bean syndrome in a child, given the risk of chronic gastrointestinal bleeding and iron-deficiency anemia.
Why it matters
Care may require multidisciplinary follow-up, and sirolimus treatment requires close monitoring.