Worldwide prevalence of diabetic ketoacidosis at diagnosis of type 1 diabetes: A systematic review and meta-analysis.
Prev MedJun 16, 2026 (epub)
Tianqi Zhang, Haichao Zhang, Shiqi Huang et al.
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In 30 seconds
This systematic review and meta-analysis examined the prevalence of diabetic ketoacidosis (DKA) at the diagnosis of type 1 diabetes (T1D) in individuals under 19 years. Analyzing data from 233 studies across 58 countries, the global prevalence of DKA was found to be 41.9%. The study highlights significant variations based on income level and demographic factors.
Key findings
- The global prevalence of DKA at T1D diagnosis is 41.9%.
- Prevalence ranges from 15.6% in Sweden to 78.5% in Thailand.
- Lower rates of DKA were observed in high-income countries at 38.6%.
- Younger age and higher female proportion correlate with increased DKA prevalence.
Why it matters
Understanding the prevalence of DKA at T1D diagnosis is crucial for clinicians to identify gaps in early detection and management. This knowledge can inform public health strategies aimed at reducing DKA incidence and improving patient outcomes.