Chyme reinfusion for management of double enterostomies and entero-atmospheric fistulae in adult patients: An updated systematic review.

In 30 seconds

This systematic review evaluated the safety and efficacy of chyme reinfusion therapy (CRT) in adult patients with double enterostomy or entero-atmospheric fistulae. Analyzing 26 reports from 23 studies involving 620 patients, the review found that 80% of patients ceased parenteral nutrition after CRT, indicating significant clinical benefits.

Key findings

• 80% of patients ceased parenteral nutrition following CRT.
• Improvements in weight or BMI were noted in 11 studies.
• Reduction in intestinal output was observed in 7 studies.
• Correction of liver function test derangement occurred in 8 studies.

Why it matters

Chyme reinfusion therapy presents a promising approach for managing intestinal failure, potentially reducing reliance on parenteral nutrition and improving patient outcomes. Understanding its benefits can guide clinicians in optimizing care for patients with complex enterostomy and fistula management.