Accuracy of Ultrasonographic Transcerebellar Diameter for Gestational Age Estimation: A Systematic Review and Meta-Analysis.
J Clin UltrasoundJun 17, 2026 (epub)
Clinical ResearchObstetrics & Gynecology
Ammar Elgadi, Mohammed Wagealla, Elwalid Idris et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the accuracy of transcerebellar diameter (TCD) for estimating gestational age (GA) in 24,825 participants across 47 studies. The analysis found a strong pooled correlation between TCD and GA, with r = 0.94 in the third trimester and r = 0.93 in the second trimester. TCD demonstrated superior correlation in IUGR pregnancies compared to other biometric measures.
Key findings
- Pooled correlation between TCD and GA was r = 0.94 in the third trimester.
- In IUGR pregnancies, TCD correlation with GA was r = 0.94, significantly higher than other measures.
- TCD showed a strong correlation of r = 0.98 when combining second and third trimesters.
- No significant differences in correlation were found between TCD and other biometric parameters.
Why it matters
Accurate gestational age estimation is crucial for prenatal care and can influence management decisions. TCD offers a reliable alternative, especially in challenging cases such as IUGR or late gestation.