Improving Medication Adherence in Kidney Transplant Recipients Through Educational Intervention and Monitoring: A Randomized Clinical Trial.
Transplant ProcJun 18, 2026 (epub)
Clinical ResearchNephrology
Carolina Heinrich de Oliveira, Anita Schweig, Beatriz Paganin Gonçalves et al.
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In 30 seconds
This randomized clinical trial evaluated the impact of educational interventions on knowledge and adherence in 59 kidney transplant recipients. The intervention group received enhanced education, resulting in significantly higher knowledge scores at one week post-discharge (7.5 vs 5.1; P < .001). However, adherence rates at six months were similar between groups (45.2% vs 39.3%; P = .697).
Key findings
- Intervention group knowledge scores were significantly higher at 1 week post-discharge (7.5 vs 5.1; P < .001).
- Adherence rates at 6 months were statistically similar between groups (45.2% vs 39.3%; P = .697).
- No significant differences in rejection rates, infections, or survival were observed during the first year.
Why it matters
Improving patient knowledge about post-transplant care is essential for promoting long-term adherence to immunosuppressive therapy, which is critical for graft survival.