Effect of Superior Laryngeal Nerve Block for Neurogenic Cough: A Single-Arm Meta-Analysis.
Otolaryngol Head Neck SurgJun 19, 2026 (epub)
Thamiris D D Cabral, Renata M Knoll, Bruno D V Vendramini et al.
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In 30 seconds
This meta-analysis evaluated the effectiveness of superior laryngeal nerve block (SLNB) in improving cough symptoms in patients with neurogenic cough, analyzing data from eight studies involving 552 patients. The results indicated a pooled proportion of subjective improvement of 74.04% and a significant reduction in Cough Severity Index scores (MD -7.37).
Key findings
- 74.04% of patients reported subjective improvement in cough after SLNB.
- Cough Severity Index scores decreased significantly by a mean difference of -7.37.
- Patients receiving 3 or more injections had a greater reduction in cough severity (MD -10.57).
- Adverse events were minimal, with serious events occurring in only 1.97% of patients.
Why it matters
Understanding the efficacy of SLNB in neurogenic cough can guide clinicians in managing this challenging condition, potentially improving patient quality of life with a relatively safe intervention.