Clustered monoallelic mosaicism in twins suggests previously unrecognized path of mutagenesis.
Jonas Böhnlein, Johann G Maass, Julia Dennig et al.
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From the abstract
We report monozygotic twins with HNRNPU-related neurodevelopmental disorder who harbor two closely spaced mosaic single-nucleotide deletions on the same allele (c.1463del [p.Pro488Glnfs∗13] and c.1466del [p.Lys489Argfs∗12]). The variants are mutually exclusive on individual DNA molecules and result in three distinct cellular lineages within each individual.