The Prevalence of Obstructive Sleep Apnoea in Schizophrenia, Bipolar Disorder and Major Depressive Disorder: A Systematic Review With Meta-Analysis.
Acta Psychiatr ScandJun 23, 2026 (epub)
Clinical ResearchPsychiatry
Constanza Sommerhoff, Marta Bort, Michele De Prisco et al.
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In 30 seconds
This systematic review and meta-analysis examined the prevalence of obstructive sleep apnoea (OSA) in individuals with severe mental illnesses (SMIs) including schizophrenia, bipolar disorder, and major depressive disorder. The study found a pooled prevalence of OSA at 41.2% in SMIs, with significantly higher odds of diagnosis compared to healthy controls (OR = 6.96; 95% CI = 2.48, 19.51; p < 0.001).
Key findings
- Pooled prevalence of OSA in SMIs was 41.2%.
- Prevalence of OSA was 38.3% in schizophrenia, 38.2% in major depressive disorder, and 35.6% in bipolar disorder.
- Individuals with SMIs had significantly higher odds of OSA diagnosis (OR = 6.96; 95% CI = 2.48, 19.51).
- 46.7% of SMI individuals were at high risk for OSA.
Why it matters
The high prevalence of obstructive sleep apnoea in individuals with severe mental illnesses underscores the need for routine screening and management in psychiatric settings to improve overall health outcomes.