Aortoesophageal Fistula: Mending the Lethal Connection-A Systematic Review and Meta-Analysis.
Noor Abu Hantash, Hazem El Beyrouti, Yousef Alghzawi et al.
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In 30 seconds
This systematic review and meta-analysis evaluated outcomes of 528 patients with aortoesophageal fistula (AEF) across various treatment strategies. The study found an overall 30-day mortality of 31.2% and 1-year mortality of 41.2%. Staged TEVAR followed by surgery showed improved survival rates but higher complication rates, highlighting the need for individualized management based on morphological severity.
Key findings
- Overall 30-day mortality was 31.2% and 1-year mortality was 41.2%.
- Staged TEVAR followed by surgery had a 30-day survival rate of 12.7% and 1-year survival of 26.1%.
- TEVAR with esophageal stenting had the lowest early mortality at 5.0%.
- Morphological severity correlated strongly with mortality and complications.
Why it matters
The high mortality rates associated with aortoesophageal fistula underscore the critical need for effective management strategies. Understanding the outcomes of different treatment approaches can guide clinicians in making informed decisions tailored to individual patient circumstances.