Primary Oral MALT Lymphoma Without Nodal or Systemic Involvement: A Rare Presentation.

Am J DermatopatholMay 11, 2026 (epub)

Elen de Souza Tolentino, Mariane Cordeiro Dos Santos, Ana Regina Casaroto Moreschi et al.

✦ AI-curated · Sources linked

Case in brief

A middle-aged patient presented with a slow-growing, asymptomatic oral lesion that was initially misidentified as an oral lipoma. Histopathological examination and immunohistochemical analysis ultimately confirmed the diagnosis of primary oral MALT lymphoma. This case emphasizes the importance of thorough evaluation in distinguishing between benign and malignant oral lesions.

What made this case unusual

The primary occurrence of MALT lymphoma in the oral cavity is exceedingly rare, making this case noteworthy for its atypical presentation.

Diagnostic / clinical pearl

Clinicians should be aware that oral lymphoid proliferations can mimic benign lesions, necessitating careful histopathological and immunohistochemical evaluation for accurate diagnosis.

Why it matters

This case underscores the diagnostic challenges of oral lymphoid lesions and the need for clinicopathological correlation to ensure appropriate management.

Source

Published in Am J Dermatopathol. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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