Quality assessment, prognostic factors, and biomarkers for brain tumor analysis: a comprehensive systematic review.
Clin Chim ActaJun 26, 2026 (epub)
P Balaji, D Devasena
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In 30 seconds
This systematic review examines the advancements in imaging technologies, prognostic factors, and biomarkers for brain tumors. It highlights the role of next-generation sequencing and radiogenomics in improving diagnosis and treatment strategies. The review emphasizes that molecular biomarkers are crucial for cancer diagnosis, treatment monitoring, and recurrence assessment.
Key findings
- Next-generation sequencing enhances molecular classification and risk stratification for brain tumors.
- Radiogenomics combines imaging phenotypes with genomic data to identify tumor signatures non-invasively.
- Liquid biopsy technologies enable non-invasive monitoring of tumor progression through ctDNA and EV analysis.
Why it matters
Understanding the integration of advanced imaging and molecular techniques can significantly improve the diagnosis and treatment of brain tumors, ultimately enhancing patient outcomes and survival rates.