Modulating sentence comprehension in people with aphasia through anodal tDCS: A double-blind randomized cross-over study.

NeuropsychologiaJun 27, 2026 (epub)

Giulia Gilardone, Mauro Viganò, Alessia Monti et al.

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In 30 seconds

This double-blind randomized cross-over study examined the impact of anodal transcranial direct current stimulation (AtDCS) combined with speech-language therapy on sentence comprehension in eight individuals with chronic nonfluent agrammatic aphasia. Results indicated that AtDCS led to greater improvements in sentence comprehension, particularly for complex structures, compared to sham stimulation, highlighting its potential as an adjunctive treatment in aphasia rehabilitation.

Key findings

  • Both AtDCS and sham conditions showed significant pre-to-post improvements in sentence comprehension.
  • AtDCS produced greater gains in comprehension of syntactically complex structures compared to sham.
  • Only the AtDCS condition resulted in significant improvements in self-perceived comprehension abilities on the CETI.

Why it matters

Enhancing sentence comprehension in individuals with aphasia can significantly improve their communication abilities and quality of life. This study suggests that integrating AtDCS with traditional therapy may offer a promising approach to rehabilitation.

Source

Published in Neuropsychologia. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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