Thoracic paravertebral nerve block combined with general anesthesia for patients undergoing minimally invasive vertebroplasty: effects on pain and lumbar function.
Int J NeurosciJul 4, 2026 (epub)
Dan Luo, Xuan Zhang, Xiao Cheng et al.
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In 30 seconds
This randomized controlled trial evaluated the effects of thoracic paravertebral nerve block (TPVB) combined with general anesthesia (GA) on pain and lumbar function in 100 patients undergoing minimally invasive vertebroplasty. The TPVB+GA group demonstrated significantly lower mean arterial pressure and heart rate, reduced blood loss, and improved pain and disability scores compared to the GA group.
Key findings
- TPVB+GA group had lower mean arterial pressure and heart rate at all measured times compared to GA alone.
- Reduced intraoperative blood loss and anesthetic consumption were observed in the TPVB+GA group.
- Lower visual analogue scale scores for pain were reported in the TPVB+GA group on postoperative days 1, 3, and 7.
- Improved Oswestry Disability Index scores were noted in the TPVB+GA group at 1 week and 1 month postoperatively.
Why it matters
The findings suggest that incorporating TPVB with general anesthesia can enhance hemodynamic stability, reduce pain, and improve recovery outcomes in patients undergoing vertebroplasty, which may influence anesthesia practices in similar surgical settings.