Chinese herbal medicine Xiangsu Hewei Granules in treating non-erosive gastroesophageal reflux disease with liver stomach stagnation heat syndrome: A multicentre, randomized, double-blind, placebo-controlled trial.
Zhi-Min Chen, Junxiang Li, Zhijun Huang et al.
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In 30 seconds
This multicentre, randomized, double-blind, placebo-controlled trial evaluated the efficacy and safety of Xiangsu Hewei Granules in 480 patients with non-erosive gastroesophageal reflux disease (NERD) and liver stomach stagnation heat syndrome. At week 8, the treatment group showed significantly higher effective rates for heartburn (76.39% vs 21.01%) and acid regurgitation (79.72% vs 23.53%) compared to placebo, indicating potential benefits of this herbal medicine.
Key findings
- The effective rate for heartburn was 76.39% in the treatment group compared to 21.01% in the control group.
- For acid regurgitation, the effective rate was 79.72% in the treatment group versus 23.53% in the control group.
- The TCM syndrome score improved in 69.23% of the treatment group compared to 30.13% in the control group.
Why it matters
The findings suggest that Xiangsu Hewei Granules may offer a beneficial alternative for managing symptoms of NERD in patients with specific traditional Chinese medicine syndromes, potentially expanding treatment options in this population.