Prognostic Value of Frailty in Aortic Surgery: A Systematic Review and Meta-Analysis Comparing Frailty Assessment Tools.
Mayara Leite Coutinho, Lucas Monteiro Delgado, Inez Ohashi Torres et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the prognostic value of preoperative frailty in 419,459 patients undergoing aortic surgery. It found that frailty significantly predicts early mortality (OR 2.20) and late mortality (HR 2.18), as well as major complications and nonhome discharge, highlighting the importance of frailty assessment in surgical risk stratification.
Key findings
- Frailty was associated with higher early mortality (OR 2.20; 95% CI 1.54-3.14).
- Frail patients had increased risks of major complications (OR 2.52; 95% CI 1.22-5.19).
- The Modified Frailty Index (mFI)-11 outperformed mFI-5 in predicting outcomes.
Why it matters
Understanding the impact of frailty on surgical outcomes can enhance risk stratification and inform perioperative decision-making, ultimately improving patient care in aortic surgery.