Comparison of the Effects of Intraoperative Pectoral Nerve Block and Local Wound Infiltration in Pain Management for Breast Cancer Surgery: A Randomized Controlled Trial.
J Perianesth NursJun 29, 2026 (epub)
Singha Sripreechapattana, Panutchaya Kongon
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In 30 seconds
This randomized controlled trial evaluated the analgesic effects of intraoperative pectoral nerve block (PECS) versus local wound infiltration in mastectomy patients. The PECS group experienced a mean time to the first analgesia request of 1,320 minutes and total morphine use of 1 mg, compared to 79 minutes and 3 mg in the control group, indicating significant opioid-sparing benefits.
Key findings
- Mean time to first analgesia request was 1,320 minutes in the PECS group vs 79 minutes in the control group (P = .013).
- Total postoperative morphine use was 1 mg in the PECS group compared to 3 mg in the local infiltration group (P = .003).
- A greater proportion of patients in the PECS group reported mild pain scores compared to the control group.
Why it matters
Effective pain management is crucial in postoperative care, particularly in breast cancer surgery. The PECS block may offer significant benefits in reducing opioid consumption and improving patient comfort, which can enhance recovery and reduce the risk of opioid-related side effects.