Long-term study to assess quality of life and cost outcomes of different delayed breast reconstruction techniques: A randomized controlled trial (GoBreast).
Fredrik Brorson, Emma Hansson, Anna Paganini et al.
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In 30 seconds
This randomized controlled trial (GoBreast) evaluated the quality of life and cost outcomes of different delayed breast reconstruction techniques in women aged 18-60, with and without prior radiotherapy. Among patients without radiotherapy (n=75), the two-stage expander (EXP) resulted in a significant positive change in health-related quality of life (HRQoL) utility value of 0.06 and fewer re-operations (2.34 vs 4.73) compared to the thoracodorsal flap with implant (TD).
Key findings
- EXP resulted in a significant HRQoL utility value change of 0.06 compared to TD.
- Patients with EXP had fewer re-operations (2.34) than those with TD (4.73).
- In patients with radiotherapy, DIEP had fewer re-operations compared to LD.
Why it matters
Understanding the cost-effectiveness and quality of life outcomes associated with different breast reconstruction techniques can guide clinicians in making informed decisions that align with patient preferences and improve overall satisfaction post-mastectomy.