99m Tc‑FAPI‑46 Scintigraphy for Staging of Non-Small Cell Lung Carcinoma.
Amin Saber Tanha, Emran Askari, Mohammad Moeini Nodeh et al.
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Case in brief
A 71-year-old man with squamous cell lung carcinoma underwent staging with CT and 99m Tc-MDP bone scintigraphy, which indicated limited skeletal involvement. However, 99m Tc-FAPI-46 scintigraphy revealed a significantly greater extent of disease, identifying extensive nodal and skeletal metastases. This led to a change in staging from oligometastatic to stage IV polymetastatic disease, impacting treatment decisions.
Diagnostic / clinical pearl
Clinicians should consider 99m Tc-FAPI-46 scintigraphy for more accurate staging of lung carcinoma, especially in cases where traditional PET/CT imaging is not feasible.
Why it matters
This case highlights the importance of advanced imaging techniques in accurately assessing disease burden, which can significantly influence treatment strategies.