Dural Manifestation of Langerhans Cell Histiocytosis​: Multimodality Imaging Approach.

Clin Nucl MedJun 29, 2026 (epub)

Nadia Nazir, Aamna Hassan, Aasma Ashraf et al.

✦ AI-curated · Sources linked

Case in brief

A 2-year-old boy presented with scalp swelling, leading to the diagnosis of Langerhans cell histiocytosis (LCH) with dural involvement. Imaging studies revealed features that mimicked meningioma or inflammatory pachymeningitis. The use of combined MRI and FDG PET imaging allowed for detailed structural assessment and evaluation of metabolic activity, aiding in the management of this rare manifestation of LCH.

What made this case unusual

Dural involvement in LCH is a rare presentation, often resembling other conditions such as meningioma.

Diagnostic / clinical pearl

Clinicians should consider LCH in pediatric patients with dural lesions that present similarly to meningioma or inflammatory conditions.

Why it matters

This case highlights the importance of multimodal imaging in differentiating LCH from other dural pathologies, which can impact treatment decisions.

Source

Published in Clin Nucl Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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