Novel RHOXF1 mutation causes male infertility by inducing severe oligoasthenozoospermia.

Reprod BiolJun 30, 2026 (epub)
Case ReportMedical GeneticsUrology

Yinshan Jin, Ying Shi, Yuanqing Cui et al.

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Condensed from the publisher's abstract. An xxcode editorial summary of this publication has not been generated yet.

From the abstract

Oligoasthenozoospermia (OAT) is a common cause of male infertility, with most OAT patients resulting from genetic defects. In this study, we recruited a severe OAT patient and his family for genetic analysis, identifying a heterozygous RHOXF1 mutation (c.412 G>A p.Glu138Lys) in the patient and his brother, inherited from their mother who carried a heterozygous RHOXF1 mutation.

Source

PubMed · PMID 42379029

Published in Reprod Biol. The text above is extracted from the publisher's own abstract and has not been edited by xxcode. For clinical decisions, review the original publication.

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