Intravenous iron administration and management of adverse events: a systematic review and Network for the Advancement of Patient Blood Management, Haemostasis and Thrombosis consensus recommendations.

In 30 seconds

This systematic review by the NATA provides consensus recommendations on the safety of intravenous iron therapy for iron deficiency and iron-deficiency anemia. It highlights key adverse events such as hypersensitivity and infusion reactions, and offers practical guidance for risk mitigation and patient management to enhance the safe use of intravenous iron in clinical settings.

Key findings

• Adverse events associated with intravenous iron include hypersensitivity, infusion reactions, and hypophosphataemia.
• Recommendations for patient counselling and formulation selection are provided to optimize safety.
• The review emphasizes the importance of systematic evaluation of safety considerations in intravenous iron administration.

Why it matters

Understanding the safety profile of intravenous iron therapy is crucial for clinicians to alleviate concerns about adverse events, thereby improving patient management of iron deficiency and anemia.