F-URS with FANS versus mPCNL for 2-3 cm UUTS: a RCT with a subgroup analysis of 2-2.5 cm stones.
Rui Wang, Xingwang Qi, Chunpeng Li et al.
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In 30 seconds
This randomized controlled trial evaluated the safety and efficacy of flexible ureteroscopy with a flexible and navigable suction ureteral access sheath (FANS) versus mini-percutaneous nephrolithotomy (mPCNL) in 326 patients with 2-3 cm upper urinary tract stones. The FANS group achieved comparable stone-free rates while demonstrating significantly less haemoglobin loss and shorter hospital stays, particularly benefiting those with stones measuring 2-2.5 cm.
Key findings
- FANS achieved comparable immediate and 1-month stone-free rates to mPCNL in the overall cohort.
- FANS was associated with significantly less haemoglobin loss and a shorter hospital stay.
- In the subgroup of stones ≥2 to <2.5 cm, FANS showed non-inferior stone-free rates compared to mPCNL.
Why it matters
The findings suggest that f-URS with FANS is a viable alternative to mPCNL for treating upper urinary tract stones, particularly for smaller stones, potentially leading to improved patient outcomes with less blood loss and shorter recovery times.