Open Versus Minimally Invasive Surgery for Congenital Diaphragmatic Hernia Repair: A Systematic Review and Meta-analysis.
Emily E Lugard, Marios Alogakos, James W F Burns et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the safety and efficacy of open surgery (OS) versus minimally invasive surgery (MIS) for congenital diaphragmatic hernia (CDH) repair in pediatric patients. Analyzing 30 studies with 6355 patients, the results indicated that while OS had a lower recurrence rate (OR: 2.09), MIS was associated with lower overall morbidity (OR: 0.51), lower mortality (OR: 0.20), and shorter hospital stays (mean difference: -4.5 days).
Key findings
- OS was associated with a lower recurrence rate (OR: 2.09, 95% CI: 1.49, 2.95).
- MIS resulted in lower overall morbidity (OR: 0.51, 95% CI: 0.37, 0.72).
- MIS had a significantly lower mortality rate (OR: 0.20, 95% CI: 0.11, 0.34).
- Patients undergoing MIS had a shorter hospital stay by an average of 4.5 days.
Why it matters
Understanding the comparative outcomes of OS and MIS for CDH repair is crucial for clinicians to make informed decisions regarding surgical approaches, particularly in pediatric populations where recovery and morbidity are significant considerations.