Paclitaxel-coated balloon therapy for refractory ureteral stenosis in a kidney transplant recipient.
Nicoletta Mancianti, Carmelo Ricci, Laura Candeloro et al.
✦ AI-curated · Sources linked
Case in brief
A kidney transplant recipient developed recurrent distal ureteral stenosis at the ureterovesical anastomosis, causing hydronephrosis and graft dysfunction. Stenosis persisted despite conventional balloon dilatation and ureteral stenting, which was complicated by recurrent urinary tract infections. Paclitaxel-coated balloon dilatation was then performed without stenting. Urinary drainage was restored, hydronephrosis resolved, and graft function improved, with no further stenting required.
What made this case unusual
Paclitaxel-coated balloon ureteroplasty was applied to a transplanted ureter as a stent-free approach after recurrent stenosis despite standard endourologic management.
Diagnostic / clinical pearl
In a transplant recipient with recurrent ureteral stenosis, persistent hydronephrosis and graft dysfunction can signal failure of conventional dilatation and stenting; this case describes a drug-coated balloon approach with subsequent improvement.
Why it matters
The outcome suggests a possible role for local antiproliferative therapy in transplant ureteral strictures, but safety and durability require further study.