The Efficacy and Safety of Clip-Assisted Endoscopic Cyanoacrylate Injection for Gastric Varices: A Systematic Review and Meta-Analysis.

Dig Dis SciJul 2, 2026 (epub)
Clinical ResearchGastroenterologyOpen access

Mohamed Abuelazm, Yousef Hawas, Belal Mohamed Hamed et al.

✦ AI-curated · Sources linked

In 30 seconds

This systematic review and meta-analysis evaluated the efficacy and safety of clip-assisted endoscopic cyanoacrylate injection (Clip-ECI) for treating gastric varices in 783 patients. The study found that Clip-ECI significantly reduced the risk of variceal rebleeding (RR: 0.24) and ectopic embolism (RR: 0.31) compared to conventional endoscopic cyanoacrylate injection (Con-ECI), while improving variceal obliteration rates.

Key findings

  • Clip-ECI reduced variceal rebleeding risk to 7.1% compared to Con-ECI.
  • Ectopic embolism rates were 2.1% in the Clip-ECI group.
  • Clip-ECI achieved a higher rate of complete variceal obliteration (RR: 1.39).
  • No significant differences in all-cause mortality or adverse events were observed.

Why it matters

The findings suggest that Clip-ECI may offer a safer and more effective alternative to Con-ECI for managing gastric varices, potentially leading to better patient outcomes and reduced complications.

Source

PubMed · PMID 42387146Free full text on PubMed Central

Published in Dig Dis Sci. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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