Extended Double Plasma Molecular Adsorption Sessions and Bilirubin Clearance: A Case Report.
Hui Ye, Yi Long Hao, Hai Nan Yang et al.
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Case in brief
A 51-year-old male with hyperbilirubinemia underwent two extended sessions of double plasma molecular adsorption treatment, each lasting over 6 hours and utilizing more than 10 L of plasma. Total bilirubin clearance was 44.6% in the first session and 34.6% in the second. The study highlighted that clearance peaked when the plasma adsorption volume matched the patient's plasma volume, with diminishing returns observed beyond this point.
Diagnostic / clinical pearl
Clinicians should note that maximizing plasma adsorption volume relative to the patient's plasma volume can optimize bilirubin clearance during double plasma molecular adsorption treatments.
Why it matters
Understanding the relationship between plasma adsorption volume and bilirubin clearance can guide treatment protocols and resource management in patients with hyperbilirubinemia.