Pleural Effusion Cytology of Metastatic Sclerosing Epithelioid Fibrosarcoma.

Diagn CytopatholJul 3, 2026 (epub)
Case ReportPathology (Anatomic & Clinical)Oncology (Medical)Open access

Daniel W Masters, Jan F Silverman

✦ AI-curated · Sources linked

Case in brief

A patient presented with a pleural effusion that was found to be metastatic sclerosing epithelioid fibrosarcoma (SEF). Cytological analysis revealed characteristic features of SEF, and immunohistochemistry, particularly MUC4, was utilized to confirm the diagnosis. The case highlights the importance of cytological evaluation in identifying this rare malignancy.

Diagnostic / clinical pearl

Clinicians should consider sclerosing epithelioid fibrosarcoma in the differential diagnosis of pleural effusions, especially when cytological features are atypical.

Source

PubMed · PMID 42397006Free full text on PubMed Central

Published in Diagn Cytopathol. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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