Modified starch powder versus epinephrine gauze for hemostasis during burn wound debridement: A randomized intra-patient trial.
Abdolkhalegh Keshavarzi, Khashayar Shahin, Nadia Rahimizadeh et al.
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In 30 seconds
This randomized intra-patient trial evaluated the efficacy of modified starch powder versus epinephrine-saturated gauze for hemostasis during burn wound debridement in 30 patients. The starch powder resulted in a significantly shorter time to hemostasis (median 1.5 min vs. 5 min; p < 0.001) and a lower bleeding flow rate, indicating its superiority in managing intraoperative hemorrhage.
Key findings
- Starch powder achieved hemostasis in a median time of 1.5 minutes compared to 5 minutes for gauze (p < 0.001).
- Bleeding flow rate was significantly lower with starch powder at 3 ml/min/TBSA% versus 7 ml/min/TBSA% (p < 0.001).
- Surgeon satisfaction was higher with starch powder, rated 'Perfect' in 76.67% of cases compared to 10% for gauze (p < 0.001).
- Wound site infection rates were significantly lower with starch powder (p = 0.027).
Why it matters
Effective hemostatic agents are crucial in surgical settings, particularly in burn wound debridement, where excessive bleeding can complicate procedures. This study suggests that modified starch powder may enhance surgical outcomes by providing faster hemostasis and improving surgeon satisfaction.