Defining neonatal encephalopathy: an international real-time Delphi consensus process.

In 30 seconds

This study established a consensus definition for neonatal encephalopathy through a real-time Delphi process involving diverse international stakeholders. The final definition describes it as a heterogeneous condition characterized by abnormal brain function, altered consciousness, and potential seizures. The survey received 235 complete responses from participants across 52 countries.

Key findings

• The final definition categorizes neonatal encephalopathy into primary, secondary, and tertiary domains.
• Participants included health-care providers, researchers, and 23 parents or caregivers.
• Responses were collected from 52 countries, with 20% from low-income and middle-income countries.
• The condition is associated with a heightened risk of morbidity and mortality.

Why it matters

Standardizing the definition of neonatal encephalopathy is crucial for improving communication among healthcare professionals and families, facilitating research, and enhancing the interpretation of clinical findings, which can ultimately lead to better patient care.