ProBIOPSY: A Multidisciplinary International Consensus on Standards for Prostate Biopsy.
Daria Chernysheva, Francesco Di Bello, Giulio Avesani et al.
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In 30 seconds
The ProBIOPSY project aimed to standardize prostate biopsy procedures through an international consensus involving 34 experts. A systematic review and a modified Delphi process led to consensus on 29 of 36 stems (81%). The consensus supports both biparametric and multiparametric MRI in the diagnostic pathway, emphasizing the need for tailored biopsy strategies for treatment planning.
Key findings
- Consensus was achieved for 29 of 36 stems (81%) regarding prostate biopsy standards.
- Both biparametric and multiparametric MRI were endorsed for the diagnostic pathway.
- A targeted ± perilesional biopsy scheme is sufficient for most local treatment planning.
- Contralateral sampling remains necessary for specific indications, particularly focal therapy.
Why it matters
Standardizing prostate biopsy procedures can enhance diagnostic accuracy and treatment planning, ultimately improving patient outcomes. Clinicians can benefit from a clearer framework for biopsy strategies tailored to individual patient needs.
What to keep in mind
Limitations include imbalances in specialty representation and heterogeneity in expertise across topics.