Cost-Utility Analyses of Systemic Treatments for Psoriasis and Psoriatic Arthritis in the UK: A Systematic Review of Modelling Methods.
Thomas S Clemmet, Duc Binh Phan, Alice Copson et al.
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In 30 seconds
This systematic review analyzed cost-utility analyses of systemic treatments for psoriasis and psoriatic arthritis in the UK. It included 68 reports detailing 35 analyses, revealing that while model structures are established, treatment sequencing and comorbidities are often inadequately addressed. The review highlights the need for improved modeling to reflect clinical practice.
Key findings
- The review included 68 reports detailing 35 cost-utility analyses for psoriasis and psoriatic arthritis.
- Most models followed a cohort-level structure with induction and maintenance phases.
- Psoriatic arthritis models considered both skin and joint symptoms, while psoriasis models focused solely on skin symptoms.
- Incomplete reporting was noted as a limitation in some models.
Why it matters
Understanding the cost-utility of treatments for psoriasis and psoriatic arthritis is crucial for healthcare decision-making, particularly in resource-limited settings like the NHS. Improved modeling can lead to better-informed treatment strategies and allocation of healthcare resources.
What to keep in mind
The review was limited by incomplete reporting for some models.