Improvement of Obesity-Related Comorbidities After Bariatric Procedures: A Network Meta-Analysis of Endoscopic Versus Surgical Interventions.
Noppachai Siranart, Panisara Fangsaard, Patavee Pajareya et al.
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In 30 seconds
This network meta-analysis evaluated the effectiveness of various bariatric procedures on obesity-related comorbidities in 61,154 patients across 55 studies. One-anastomosis gastric bypass (OAGB) showed significant superiority in improving diabetes mellitus (OR: 2.47) and hypertension compared to sleeve gastrectomy. The study highlights the need for further randomized controlled trials to clarify these findings.
Key findings
- OAGB was significantly superior to RYGB and SG for diabetes mellitus improvement (OR: 2.47).
- OAGB and RYGB showed greater hypertension improvement compared to SG (OR: 1.84 and OR: 1.30, respectively).
- OAGB and RYGB had significantly higher odds of improving GERD compared to SG (OR: 5.48 and OR: 3.82, respectively).
- SADI ranked highest for diabetes mellitus improvement with a P-score of 0.932.
Why it matters
Understanding the comparative effectiveness of bariatric procedures is crucial for clinicians to optimize treatment strategies for obesity-related comorbidities, potentially leading to better patient outcomes and tailored interventions.
What to keep in mind
Outcomes were heterogeneously defined across studies, and evidence is limited.