Ketamine for Cancer-Related Pain in Palliative Care: A Systematic Review of Clinical Use and Safety.
Catarina Vitorino-Afonso, Paulo Reis-Pina
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From the abstract
Ketamine has emerged as an adjuvant for opioid-refractory cancer-related pain in palliative care, but evidence remains limited. This systematic review examined ketamine use for cancer-related pain in palliative and end-of-life care. MEDLINE, Cochrane Library, Web of Science, and Scopus were searched for English-language studies (publication 2017-2025).