Long-term efficacy of cognitive behavioural therapy for insomnia (CBT-I) on depressive symptoms: A systematic review and meta-analysis of randomised controlled trials.
Sleep Med RevJul 9, 2026 (epub)
Clinical ResearchPsychiatry
Valeria Fiori, Caterina Lombardo, Chiara Baglioni et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the long-term effects of cognitive behavioural therapy for insomnia (CBT-I) on depressive symptoms in adults with insomnia. Analyzing 53 RCTs involving 13,608 individuals, the study found that CBT-I significantly reduced depressive symptoms at 3, 6, and 12 months post-treatment, with effect sizes of -0.35, -0.32, and -0.25, respectively.
Key findings
- CBT-I reduced depressive symptoms at 3 months with an effect size of -0.35.
- At 6 months, CBT-I maintained a significant effect on depressive symptoms with an effect size of -0.32.
- The effect of CBT-I on depressive symptoms at 12 months had an effect size of -0.25.
Why it matters
Understanding the long-term efficacy of CBT-I on depressive symptoms is crucial for clinicians managing patients with insomnia, as it highlights the potential for sustained mental health benefits following treatment.