Adrenocortical oncocytoma manifesting as primary aldosteronism: a case report.
Qun Ji, Yikai Liu, Yuhai Zhang et al.
✦ AI-curated · Sources linked
Case in brief
A 44-year-old man presented with severe hypertension and hypokalaemia, revealing a right adrenal lesion on imaging. Evaluation confirmed primary aldosteronism, with adrenal venous sampling indicating right-sided aldosterone secretion. Following laparoscopic right adrenalectomy, histopathology identified an adrenocortical oncocytoma. The patient experienced biochemical correction and clinical improvement, with positive outcomes at 19-month follow-up.
What made this case unusual
This case highlights an adrenocortical oncocytoma presenting as primary aldosteronism, a notably rare occurrence, as most oncocytomas are non-functioning.
Diagnostic / clinical pearl
Clinicians should consider adrenocortical oncocytoma in patients with primary aldosteronism, especially when typical imaging and biochemical evaluations are present.
Why it matters
Understanding the potential for oncocytomas to secrete aldosterone expands the differential diagnosis for primary aldosteronism and underscores the importance of surgical intervention.