Advances in Traditional Chinese Medicine for Diabetic Glaucoma: A Systematic Review From Holistic Pathogenesis to Multi-Target Interventions.
Jinshen Liu, Yujia Yu, Chen Hu et al.
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In 30 seconds
This systematic review examines the role of Traditional Chinese Medicine (TCM) in managing diabetic glaucoma, a complication of diabetes characterized by neurodegeneration. It highlights the multi-target interventions of TCM, particularly the Si-Hua formula, in addressing oxidative stress and inflammation. The review establishes a correlation between TCM syndromes and modern pathological mechanisms, emphasizing the potential of TCM in neuroprotection and disease progression delay.
Key findings
- TCM demonstrates unique advantages through multi-component, multi-target, and multi-pathway synergistic regulation.
- The Si-Hua formula's components show significant regulatory intensity on key signaling pathways.
- Key mechanisms include antioxidant, anti-inflammatory, and microcirculation-improving effects.
- Network pharmacology methods visually present the 'component-target-pathway' interaction network.
Why it matters
Understanding the integration of TCM with modern medical approaches could enhance treatment strategies for diabetic glaucoma, particularly in providing neuroprotection and addressing complex disease mechanisms that conventional therapies may not fully manage.