Scleral lens peripheral modifications and regional variations in corneal oedema.
Cont Lens Anterior EyeJul 18, 2026 (epub)
Clinical ResearchOphthalmology
Asif Iqbal, Damien Fisher, David Alonso-Caneiro et al.
✦ AI-curated · Sources linked
In 30 seconds
This randomized controlled trial examined the impact of different peripheral scleral lens designs on corneal oedema in nine healthy participants. The study found that lenses with toric landing zones and peripheral channels resulted in significantly less peripheral corneal oedema compared to spherical designs, with the channel design also showing reduced central oedema (1.57 ± 0.45% less, p = 0.04).
Key findings
- The channel lens design showed 1.57 ± 0.45% less central oedema compared to the toric design (p = 0.04).
- The toric lens resulted in 2.66 ± 0.66% less peripheral oedema than the spherical design (p = 0.02).
- The channel design exhibited 3.39 ± 0.97% less peripheral oedema compared to the spherical design (p = 0.04).
- A significant correlation was found between peripheral tear exchange and peripheral oedema (r = -0.61, p < 0.001).
Why it matters
Understanding how different scleral lens designs affect corneal oedema can help clinicians optimize lens fitting and improve patient comfort. Enhanced tear exchange may reduce complications associated with lens wear.