The effect of Intense Pulsed Light therapy on eyelid bacterial load in contact lens discomfort.
Srikanth Dumpati, Fatima Iqbal, Ajay Kumar Vijay et al.
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In 30 seconds
This randomized controlled trial assessed the impact of Intense Pulsed Light (IPL) therapy on eyelid microbiota in symptomatic contact lens wearers. Eighteen participants completed the study, revealing a significant reduction in bacterial load (CFU/swab) in the IPL group from day 0 to day 42, particularly for total gram-positive cocci and coagulase-negative staphylococci (p < 0.001).
Key findings
- IPL therapy reduced total gram-positive cocci from 174.0 ± 11.5 to 122.0 ± 8.4 CFU/swab by day 42 (p < 0.001).
- Total gram-positive rods decreased from 174.0 ± 8.2 to 126.0 ± 8.2 CFU/swab by day 42 (p < 0.001).
- Coagulase-negative staphylococci counts dropped from 174.0 ± 12.2 to 122.0 ± 10.0 CFU/swab by day 42 (p < 0.001).
- By day 90, bacterial counts partially rebounded towards baseline levels.
Why it matters
Understanding the effects of IPL therapy on eyelid microbiota can inform treatment strategies for contact lens discomfort, potentially improving patient outcomes and comfort in symptomatic wearers.