Comparative Effects of Four Dietary Approaches on Symptom Severity and Quality of Life in Irritable Bowel Syndrome: A Randomized Controlled Trial.
Nezihe Otay Lule, Mine Yurttagul, Abdullah Emre Yildirim et al.
✦ AI-curated · Sources linked
In 30 seconds
This randomized controlled trial evaluated the effects of four dietary approaches on symptom severity and quality of life in adults with irritable bowel syndrome (IBS). Participants aged 19-65 were assigned to a traditional diet, low-FODMAP diet, gluten-free diet, or a combined low-FODMAP gluten-free diet for four weeks. The low-FODMAP and combined diets significantly reduced IBS symptom severity compared to the traditional diet, with a p-value of 0.002.
Key findings
- IBS Symptom Severity Score decreased significantly in all groups (p ≤ 0.004).
- LFD and LFGFD groups showed greater reductions in IBS-SSS compared to the TD group (p = 0.002).
- 61.5% of participants in the TD group achieved clinically meaningful symptom improvement compared to all in LFD, GFD, and LFGFD groups (p = 0.001).
- No significant between-group differences in quality of life were detected (p = 0.082).
Why it matters
Understanding the comparative effectiveness of dietary interventions for IBS can guide clinicians in recommending personalized dietary strategies that optimize symptom management and enhance patients' quality of life.