Integrated exposure-based therapy for co-occurring post-traumatic stress and substance use among young people: a randomized controlled trial.

Eur J PsychotraumatolJul 21, 2026 (epub)
Clinical ResearchPsychiatryOpen access

Katherine L Mills, Natalie Peach, Ivana Kihas et al.

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In 30 seconds

This randomized controlled trial evaluated the efficacy of the integrated exposure-based treatment COPE-A for post-traumatic stress disorder (PTSD) and substance use disorder (SUD) in young people aged 12-25. Conducted in Sydney, Australia, with 55 participants, COPE-A resulted in significantly greater reductions in PTSD symptom severity (mean difference -9.82) and diagnosis at 4 months compared to supportive counseling (PCT), with effects maintained at 12 months.

Key findings

  • COPE-A led to a mean difference of -9.82 in PTSD symptom severity at 4 months.
  • At 4 months, only 20.0% of COPE-A participants met PTSD diagnostic criteria compared to 66.7% in PCT.
  • Client satisfaction scores were significantly higher in COPE-A than in PCT.
  • Both treatments showed reductions in substance use severity, but no significant between-group differences.

Why it matters

The study highlights the potential for integrated treatments to effectively address co-occurring PTSD and SUD in young populations, which is crucial given the developmental onset of these disorders. Improved outcomes in a shorter timeframe may enhance treatment engagement and overall recovery.

Source

Published in Eur J Psychotraumatol. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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