Efficacy and Safety of Endoscopic Treatment for Chronic Hemorrhagic Radiation Enteropathy: A Systematic Review and Meta-analysis.
Yue Sun, Yuhang Yin, Siqi Jia et al.
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In 30 seconds
This systematic review and meta-analysis evaluated the efficacy and safety of endoscopic treatments for chronic hemorrhagic radiation enteropathy in 2626 patients. The study found that argon plasma coagulation (APC) achieved a clinical success rate of 95% and a mean hemoglobin increase of 20.61 g/L, indicating high effectiveness and safety of endoscopic interventions.
Key findings
- Argon plasma coagulation (APC) had a clinical success rate of 95% and a mean hemoglobin increase of 20.61 g/L.
- Radiofrequency ablation achieved a clinical success rate of 100% with a mean hemoglobin increase of 20.33 g/L.
- After laser treatment, the clinical success rate was 87%, and for cryotherapy, it was 92%.
Why it matters
Chronic hemorrhagic radiation enteropathy is a significant complication of pelvic radiotherapy, and effective management is crucial. This review highlights the potential of endoscopic treatments to improve patient outcomes and reduce the need for more invasive procedures.