Multiple myeloma diagnosed after contrast-enhanced computed tomography without renal complications: a case report with literature review.
Keiko Kudoh, Takaharu Kudoh, Yasuhiko Morita et al.
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Case in brief
A 77-year-old woman presented with numbness of the right lower lip, leading to a panoramic radiography that revealed a radiolucent lesion in the right mandible. A contrast-enhanced CT scan, initially performed to investigate suspected jaw carcinoma, showed enhancing masses in the mandible and skull, suggesting multiple myeloma (MM). A biopsy confirmed plasma cell myeloma, and systemic chemotherapy led to tumor regression without renal complications.
Diagnostic / clinical pearl
This case highlights that contrast-enhanced CT can be safely used in patients with multiple myeloma and normal renal function, potentially improving diagnostic accuracy for suspected malignancies.
Why it matters
The findings suggest that the risk of contrast-induced nephropathy may be lower than previously thought in patients with multiple myeloma who do not have renal dysfunction, warranting further investigation into the safety of contrast use in this population.